POST Online Media Lite Edition


NEWLY REPORTED COVID-19 CASES IN LAST 24 HOURS (9.27.2021, 10:31am CEST, WHO):   India 26,041    Brazil 15,688    United Kingdom 29,746    Russia 22,498    Turkey 26,145    France 6,012    Iran 13,792    Columbia 1,740    Italy 3,519    Germany 7,774    Mexico 9,697    South Africa 1,634    Philippines 20,755    Ukraine 4,647    Malaysia 13,104    Netherlands 1,625    Iraq 2,139    Japan 2,288    Thailand 10,288    Pakistan 1,780    Kazakhstan 2,379    Serbia 6,192    Vietnam 10,011    Austria 2,029    Greece 1,814    Georgia 1,132    Belarus 1,987    Bulgaria 1,038    Azerbaijan 1,099    Palestine 1,069    Ireland 1,335    Venezuela 1,191    Ethiopia 1,187    Lithuania 1,277    South Korea 2,383    Mongolia 1,991    Slovenia 1,005    China 51    Singapore 1,939    New Zealand 12    Australia 1,770   

Key to long-term malaria vaccine unlocked, say Australian researchers

Staff Writer |
Australian researchers from Queensland believe they have found the key behind developing a long-term vaccine for malaria.

Article continues below

Scientists at the QIMR Berghofer Medical Research Institute announced their results investigating how activating immune cells known as CD8+ T cells could protect against the disease.

"We compared two groups of mice," head of the Molecular Immunology Laboratory, Michelle Wykes said.

"The first was a control group. In the other group we activated the CD8+ T cells by removing a molecule that otherwise puts the brakes on this immune cell."

She noted that compared to the control group, the experimental group was much more resistant to the malaria.

"About five months later, the experimental group had lower levels of antibodies than the control group, but was still resistant to malaria," Wykes said.

"However, when we depleted their CD8+ immune cells, those same mice lost resistance to malaria."

Wykes noted it was the first time there had been evidence to show that CD8+ immune were crucial for protecting against blood stage malaria.

"In other words, we've found that antibodies on their own aren't enough to maintain protection against malaria."

The World Health Organization estimated malaria caused the death of 438,000 people and infected 214 million people worldwide in 2015.

What to read next

Malaria vaccine target's invasion partner uncovered
Genetic tweaks in mosquitoes might curb malaria transmission
New drug effective against malaria