Cancer cells play hide-and-seek with immune system
The researchers discovered that as a result of the immune reaction new tumor cells are formed that have far fewer or even none of the DNA modifications that the immune system can recognise.
This is how the tumor tries to escape the immune reaction. However, the immune system can learn to recognise new DNA modifications.
By treating cancer patients with a different form of immunotherapy, it should be possible to switch off the modified tumor cells as well, the researchers conclude.
Immunotherapy is a cancer treatment whereby the patient's own immune system is activated to trace and destroy cancer cells. ■