POST Online Media Lite Edition


For many, lactose intolerance may be bloated myth

Staff writer |
According to new research, lactose intolerance may be a myth for many, with resulting symptoms from drinking milk most likely an inflammatory response to the A1 protein found in conventional cow's milk.

Article continues below

Published in the U.K.-based Nutrition Journal, the study led by Professor Sun Jianqin from Huadong Hospital, an affiliate of the Fudan University in Shanghai, China compared the impact of humans drinking conventional cow's milk – milk with the A1-protein – to that of milk that is A1-protein free.

China has been chosen for clinical research due to the high prevalence of lactose intolerance in the country (nearly 90% of population reports lactose intolerance).

First human study-based research testing the effects of the A1 versus A2 protein types on participants with clinically diagnosed lactase deficiency/lactose intolerance.

Conventional cow's milk (containing A1 protein type) caused significantly higher gastrointestinal inflammation, stool transit delays, and elevated blood markers for inflammation and immune response compared to milk containing only the A2 protein (free-from the A1 protein type).

The study was supported by The a2 Milk Company, an Australian milk company specializing in milk from cows selected because they naturally produce only milk containing the A2 protein type.

After overwhelming success in Australia and more recently growing popularity in China, a2 Milk launched in the United States, with major plans for nationwide distribution.

The a2 Milk Company entered select U.S. markets, first in California, and is available in all major grocers, including Whole Foods, Sprouts and Fresh Market nationally.

"This research confirms the post-dairy digestive discomfort may not always be the result of lactose intolerance," said Jeff O'Neill, president, The a2 Milk Company, U.S.

"Lactose is what usually takes the blame for millions of people worldwide with digestive issues associated with ordinary cow's milk, leading many to give up milk altogether. The evidence is strong that an inflammatory response to the A1 protein may be the issue for a large proportion of people."

Originally, all cows only produced milk containing the A2 type of beta-casein protein. However, after domestication, another milk protein type – A1 protein type – appeared in European herds and spread along with human migration. A1 protein is contained in the vast majority of cow's milk consumed in the U.S. today.

A 2009 study published in Nutrition Today, found approximately 1-in-4 Americans (significantly higher proportions within Asian, African American and Hispanic populations) experience digestive issues when consuming conventional cow's milk, with the majority incorrectly associating these symptoms to lactose intolerance. The new China based research further supports these findings.

This Chinese research is the first human-based research testing the effects of the A1 versus A2 protein types on participants, half who were clinically confirmed as truly having issues with lactose digestion.

The trial found milk containing only the A2 protein type caused no gastrointestinal disturbance in any study participants, including those confirmed to have issues digesting lactose.

Study participants who drank conventional cow's milk (containing the A1 protein), experienced elevated gastro-intestinal inflammation, stool transit delays, and elevated markers for inflammation and immune response.

When participants drank milk containing only the A2 protein, it was significantly gentler on their digestive system, with less inflammation associated with bloating and abdominal pain.

According to contributing author, Associate Professor Xia, Gastroenterologist at the Shanghai Jiaotong University School of Medicine, and Adjunct Associate Professor at Johns Hopkins University School of Medicine, "These are significant findings for those who believe they suffer from lactose intolerance.

"The research suggests milk that only contains the A2 type protein (A2 beta-casein) has a natural affinity with the human body and digestion. Gut inflammation caused by the A1 type protein can be avoided by consuming milk products with only the A2 type protein.

"With so many people believing they are lactose intolerant, both in China and around the world, the findings are truly noteworthy."

What to read next

Food sensitivity and intolerance may be mistaken for allergic reaction in children
Heredity explains African-American diseases paradox

Lomar Shipping announces acquisition of Carl Büttner Holding

Lomar Shipping, a maritime subsidiary of Libra Group, has acquired the Bremen, Germany-based Carl Büttner Holding.


Pfizer completes $11.6bn acquisition of Biohaven Pharmaceuticals
United Airlines suspends service to New York JFK
Companies increasingly pessimistic about Swiss economy
EU antitrust watchdog in talks with Germany over 200 bln euro support plan


Explosion in chemical factory in Uzbekistan

Indiana AG: Make sure your social media accounts are safe after you die
U.S.: Variety of weather hazards to start off the week
Hurricane Orlene expected to hit Mexico
Russian nuclear submarine disappeared from NATO radars
Swedish Coast Guard issues update on gas leaks in Baltics


Plan for big boost in GP training numbers in New Zealand

World’s tallest timber apartment tower to be built in Zanzibar
950,000 Singaporean households to get rebate for up to 10 months of bills
Seven vessels with foodstuffs leave Ukrainian ports
Site of UK’s first fusion energy plant selected
AG Ferguson: Half-billion dollars to fight opioid epidemic will start flowing December 1

Trending Now

Alfa Laval signs global partnership agreement with Spirax Sarco

World’s tallest timber apartment tower to be built in Zanzibar

Rockwell Automation to buy CUBIC

Alexion, AstraZeneca Rare Disease to acquire LogicBio Therapeutics


There must be no return to austerity, says Murphy

U.S. Treasury takes additional sanctions actions across Bosnia and Herzegovina
Libya, Türkiye sign MoU for oil, gas cooperation
Commission approves €800 million Greek scheme to support non-household electricity consumers
Commission approves €134 million German measure to support BASF in production of renewable hydrogen
North Dakota Governor leads trade and investment mission to Japan

Today We Recommend

950,000 Singaporean households to get rebate for up to 10 months of bills


ABB wins $170 million in orders from Stadler Valencia to enhance Europe’s railway network

PwC expects remainder of 2022 and 2023 to be challenging

PwC announces record global revenues of $50 billion


ORLEN Group launching new petrochemical product

Cambrex announces stability storage expansions in Ireland and Belgium
Excelerate Energy finalizes agreement with Hyundai Heavy Industries for for floating regasification and storage unit
LyondellBasell starts production at its Frankfurt site
Alfa Laval signs global partnership agreement with Spirax Sarco
Duke Energy commits $250,000 to support Hurricane Ian relief efforts


Ara Partners hires Teresa O'Flynn as partner and co-lead of infrastructure strategy

Kimberly Nelson named president of Kemin Nutrisurance
Discovery Life Sciences appoints Suso J. Platero as chief scientific officer
Sandeep Johri joins LambdaTest board
Skyresponse appoints Mats Berthem as new CEO
Phathom Pharmaceuticals appoints James Toppe to board


U.S. construction spending decreases more than expected in August

Manufacturing PMI at 50.9% September
PwC expects remainder of 2022 and 2023 to be challenging
Turkish inflation rate hits 24-year high of 83%
Japan consumer confidence deteriorates but remains in positive territory in September
Poland inflation comes in at highest level since February 1997 in September


PwC announces record global revenues of $50 billion

AllianceBernstein's fund net assets 377,335,035
CarMax Q2 revenues $8.1 billion
Rite Aid Q2 net loss $331.3 million
NIKE Q1 2023 revenues $12.7 billion
Morrisons Q3 revenue up 4.5%


Micromanaging is the worst enemy of efficiency and teamwork

Niger set to monetize massive gas reserves through Saharan natural gas pipeline
Putting the brakes on EV folly that choked the market
Oil discovery in Kavango Basin may mean huge benefits for Namibians
Cape Town and Dubai battle over Africa's energy future
Is America going to lose its superpower status?


Utah confirms additional 3 cases of HPAI on turkey farms in Sanpete County

Oregon: HPAI confirmed in Douglas County backyard flock
Russia: Over 23 thousand tons of grain, processing products sent for export from Primorye
Netherlands to cull around 102,000 chickens to contain bird flu
Rosselkhoznadzor found about 73 tons of infected vegetables and fruits in Dagestan
Farmers in Guyana to training to improve and sustain their incomes


Forget everything you know about hiring people

Cybervetting can have pronounced impact on workforce by broadening discrimination
Female managers pay fairer
Pitch quality of CEO voices rests entirely on gender
Employee turnover costs more than you think
51% of supply chain leaders increased number of network locations


Kim Kardashian to pay $1.26 million for unlawfully touting crypto security after SEC charges

SEC charges two Canadian programmers for GlobeNewswire with insider trading
Barclays agrees to $361 million settlement to resolve SEC charges relating to over-issuances of securities
Justice department announces total distribution of over $4 billion to victims of Madoff Ponzi Scheme
Bank of Ireland fined EUR100.5 million over tracker mortgage dispute
11 financial institutions to pay over $710m for recordkeeping and supervision failures, unapproved communication



Come to the astronomy capital of the world and meet the stars

All New Zealand fans of all things home and garden are welcome to Hamilton
Sanctuary Cap Cana opens in Dominican Republic
Skate with Olympic star Patrick Chan at Vancouver rinks
Annual Peanut Festival in Aubrey, Tx. is celebration of past and joy of present
Anantara Grand Hotel Krasnapolsky Amsterdam opens


2023 Ford F-Series Super Duty, built like never before

Caterham Super Sevens, true joy of ride
New Ford Mustang brings digital cockpit, new engines and style
Ram 1500 Limited Elite Edition joins lineup for 2023
2023 GMC Canyon AT4X, new midsize truck
Shelby Code Red, $210,000+ to upgrade your Ford Mustang


Noritake tableware, to pass down to the new generation as an heirloom

Tecnografica wallcoverings from the land of ceramic
Poliform, kitchens for extraordinary homes
Luxury vinyl tiles, ideal combination of everything
LED lamps, long-lasting light for every space in your home
Clean and luxurious men's watches


Technics SL-1200, the legend keeps spinning

Leica S3, made in Germany for great pictures
Sennheiser HD 300 PROtect, pro headphones that protect your ears
HP Dragonfly Folio G3, very very good laptop for business users
Nokia PureBook Fold and PureBook Lite, flexibility and stylish design
Tascam 202MKVII, professional dual cassette deck


Roche launches its next-generation SARS-CoV-2 Rapid Antibody Test

FDA approves Taiho's LYTGOBI (futibatinib) tablets
New recommendations for terlipressin-containing medicines in treatment of hepatorenal syndrome
Singapore authorises Pfizer COVID-19 vaccine for children aged 6 months through 4 years
Russia’s Vector Center developing mRNA coronavirus vaccine
Shionogi says COVID pill resolves Omicron symptoms faster


Three scientists share Nobel Prize in Physics for work in quantum mechanics

Swedish scientist Svante Pääbo wins Nobel Prize in medicine for discoveries on human evolution
First probable impact crater discovered in Spain
New evidence for liquid water beneath south polar ice cap of Mars
Potential first traces of the universe's earliest stars
New archaeology dives into mysterious demise of Neanderthals