Antiviral medicines for the treatment of COVID-19 will be evaluated through a new national study called PANORAMIC, run by the University of Oxford.
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The UK wide study will prioritise those at greater risk of being severely ill if they test positive for COVID-19. Eligibility for the study is therefore limited to those who meet certain criteria.
The study is open to people aged 50 and above, or 18-49 with certain underlying health conditions which make them more vulnerable to COVID-19. They must also have started to experience COVID-19 symptoms within the past five days and have recorded a positive PCR test.
In addition to the study, all people considered as extremely high risk of becoming severely ill with COVID-19, and who have tested positive, will be able to access a monoclonal antibody or, if not appropriate, an antiviral treatment, from 16 December.
In the coming weeks letters will be sent to those eligible with further information. Details on who is eligible can also be found on NHS Inform, and from 16 December a dedicated contact number will be available for each health board to provide further information on how to get access to the medicines.
These treatments are in addition to vaccinations which still remain the best way to protect everyone.
Scotland’s Chief Medical Officer Dr Gregor Smith said:
“This University of Oxford study will test whether new antiviral treatments for COVID-19 can help people in the early stages of the illness recover faster and therefore reduce the number of people being admitted to hospital.
“The results from the national study will give us a clearer understanding on how antivirals work in the UK population, which will allow the NHS to better plan how to make COVID-19 antivirals available for those who would benefit from them the most. We will provide further detail on plans for wider availability of antivirals in due course.
“I would encourage people in Scotland to take part if they are eligible. You may be contacted about taking part by a health care professional if you have a positive PCR result, or you can register yourself via the Oxford University website www.panoramictrial.org.
“The treatment is tablets taken orally as soon as possible after getting a COVID-19 infection to stop the illness from getting worse."
The University of Oxford PANORAMIC national study will be open to people who meet all the following criteria:
Have received a positive PCR test for COVID-19.
Feel unwell with symptoms of COVID-19 that started in the last five days.
With an underlying medical condition that can increase chance of having severe COVID-19:
Chronic respiratory disease including chronic obstructive pulmonary disease (COPD), cystic fibrosis and asthma requiring at least daily use of preventative and/or reliever medication
Chronic heart or vascular disease
Chronic kidney disease
Chronic liver disease
Chronic neurological disease including dementia, stroke, epilepsy
Severe and profound learning disability
Down’s syndrome
Diabetes mellitus
Immunosuppression due to disease or treatment e.g. sickle cell, HIV, cancer, chemotherapy
Solid organ, bone marrow, or stem cell transplant recipients
Morbid obesity (BMI >35)
Severe mental illness
Care home resident
Considered by recruiting clinician to be clinically vulnerable. ■