Three drugs fairly effective on Wuhan coronavirus on cellular level
Topics: WUHAN CORONAVIRUS
The three drugs are Remdesivir, Chloroquine and Ritonavir. They are now under relevant procedures to gain approval for clinical use, said Hubei Daily yesterday.
The discovery was jointly made by researchers from the Academy of Military Medical Sciences and the Wuhan Institute of Virology (WIV) under the Chinese Academy of Sciences (CAS).
Previously, researchers from the Shanghai Institute of Materia Medica under the CAS and ShanghaiTech University jointly selected 30 existing drug candidates, biologically active natural products and traditional Chinese medicines which may have therapeutic effects on the novel coronavirus.
The candidates included 12 anti HIV drugs like Indinavir, Saquinavir, Lopinavir and Carfilzomib, two anti respiratory syncytial virus drugs, an anti-schizophrenia drug, an immunosuppressant, as well as traditional Chinese medicines including Polygonum cuspidatum.
Since the outbreak of Wuhan coronavirus, several research teams led by the WIV have carried out research on five aspects, including rapid detection products, antiviral drugs and vaccines, animal traceability research, as well as etiology and epidemiology research.
The genome sequencing of the novel coronavirus is as high as 96 percent identical with a type of coronavirus from bats, the team said, adding that the new coronavirus enters the receptor using the same cells with SARS virus.
The latest finding provides critical evidence to study the pathology and origin of the virus, it said. ■