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Texas reports possibly U.S. first human case of bird flu linked to cattle

Christian Fernsby |
A person in the United States has tested positive for highly pathogenic avian influenza (HPAI) A(H5N1) virus (“H5N1 bird flu”), as reported by Texas and confirmed by CDC.

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This person had exposure to dairy cattle in Texas presumed to be infected with HPAI A(H5N1) viruses. The patient reported eye redness consistent with conjunctivitis as their only symptom, and is recovering.

The patient was told to isolate and is being treated with an antiviral drug for flu. This infection does not change the H5N1 bird flu human health risk assessment for the U.S. general public, which CDC considers to be low.

CDC is working with state health departments to continue to monitor workers who may have been in contact with infected or potentially infected birds/animals and test those people who develop symptoms.

CDC also has recommendations for clinicians on monitoring, testing, and antiviral treatment for patients with suspected or confirmed avian influenza A virus infections.

This is the second person reported to have tested positive for influenza A(H5N1) viruses in the United States.

A previous human case occurred in 2022 in Colorado.

Human infections with avian influenza A viruses, including A(H5N1) viruses, are uncommon but have occurred sporadically worldwide. CDC has been monitoring for illness among people exposed to H5 virus-infected birds since outbreaks were first detected in U.S. wild birds and poultry in late 2021.

Human illnesses with H5N1 bird flu have ranged from mild (e.g., eye infection, upper respiratory symptoms) to severe illness (e.g., pneumonia) that have resulted in death in other countries.

HPAI in dairy cows was first reported in Texas and Kansas by the U.S. Department of Agriculture (USDA) on March 25, 2024.

Unpasteurized milk from sick cattle collected from two dairy farms in Kansas and one in Texas, as well as a throat swab from a cow in another dairy in Texas, tested positive for HPAI A(H5) viruses of the genetic clade 2.3.4.4b, which is the same clade that is widespread among birds globally.

On March 29, 2024, USDA’s National Veterinary Services Laboratories (NVSL) confirmed HPAI in a Michigan dairy herd that had recently received cows from Texas.

Candidate vaccine viruses (CVVs) developed against related clade 2.3.4.4b viruses are available for vaccine manufacturing if necessary and preliminary analysis indicates that they may provide reasonable protection against H5N1 influenza viruses.

Seasonal flu vaccines do not provide protection against these viruses. Analysis of virus samples is ongoing.


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